MS Drug Prevented Fatal Heart Condition In Lab Study
A drug used to treat multiple sclerosis may also be effective at preventing and reversing the leading cause of heart attack, a new study has found. Scientists found that Gilenya, a drug recently approved in the US for treating MS, was effective at reversing the symptoms of ventricular hypertrophy in mice...
Muscle Endurance Tests Can Detect Abormalities In The Early Stages Of Multiple Sclerosis
Multiple sclerosis (MS), a neurodegenerative disease, causes periodic attacks of neurologic symptoms such as limb weakness and mobility defects. And while MS patients' walking abilities and muscle strength are examined on a regular basis, doctors have yet to determine when the lower limb muscles begin to deteriorate...
New Standard For Vitamin D Testing To Ensure Accurate Test Results
At a time of increasing concern about low vitamin D levels in the world's population and increased use of blood tests for the vitamin, scientists are reporting development of a much-needed reference material to assure that measurements of vitamin D levels are accurate. The report appears in ACS' journal Analytical Chemistry...
Rebif® For Early Symptoms Of Multiple Sclerosis, UK
Rebif® (interferon beta-1a), a disease-modifying medication used to treat relapsing forms of multiple Sclerosis (MS), is now available in the UK to treat individuals with clinically isolated syndrome (CIS), a potential early indicator of MS, announced Merck Serono, a division of Merck KGaA, Darmstadt, Germany...
Greater Brain Activation Reported After Cognitive Rehabilitation For Multiple Sclerosis
Neuroscientists at Kessler Foundation have documented increased cerebral activation in patients with multiple sclerosis (MS) following memory retraining using the modified Story Memory Technique (mSMT)...
Brain Support Cells From Umbilical Cord Stem Cells
For the first time ever, stem cells from umbilical cords have been converted into other types of cells, which may eventually lead to new treatment options for spinal cord injuries and multiple sclerosis, among other nervous system diseases...
Clues To Causes Of Nerve Cell Degeneration Provided By Spasticity Gene Finding
The discovery of a gene that causes a form of hereditary spastic paraplegia (HSP) may provide scientists with an important insight into what causes axons, the stems of our nerve cells, to degenerate in conditions such as multiple sclerosis...
Study Suggests Potential For Reversing Age-Associated Effects In Multiple Sclerosis Patients
New research highlights the possibility of reversing ageing in the central nervous system for multiple sclerosis (MS) patients. The study is published in the journal Cell Stem Cell. As we get older, our bodies' ability to regenerate decreases...
Research Proving Link Between Virus And MS Could Point The Way To Treatment And Prevention
A new study from researchers at Queen Mary, University of London shows how a particular virus tricks the immune system into triggering inflammation and nerve cell damage in the brain, which is known to cause MS...
UTHealth Researchers Link Multiple Sclerosis To Different Area Of Brain
Radiology researchers at The University of Texas Health Science Center at Houston (UTHealth) have found evidence that multiple sclerosis affects an area of the brain that controls cognitive, sensory and motor functioning apart from the disabling damage caused by the disease's visible lesions...
Researcher Contends Multiple Sclerosis Is Not A Disease Of The Immune System
An article published Friday Dec. 23 in the December 2011 issue of The Quarterly Review of Biology argues that multiple sclerosis, long viewed as primarily an autoimmune disease, is not actually a disease of the immune system. Dr...
Genzyme Reports Top-line Results For TENERE Study Of Oral Teriflunomide In Relapsing Multiple Sclerosis
Sanofi (EURONEXT: SAN and NYSE: SNY) and its subsidiary Genzyme reported top-line results from TENERE, a Phase III clinical trial comparing the effectiveness, safety and tolerability of once-daily oral teriflunomide to interferon beta-1a (Rebif®), an approved injectable therapy, in people with relapsing forms of multiple sclerosis (RMS)...
Monitoring MS Progression Using Powerful MRI To Track Iron Levels In The Brain
Medical researchers at the University of Alberta have discovered a new way to track the progression of multiple sclerosis (MS) in those living with the disease, by using a powerful, triple strength MRI to track increasing levels of iron found in brain tissue...
Intestine Crucial To Function Of Immune Cells, Research Shows
Researchers at the University of Toronto have found an explanation for how the intestinal tract influences a key component of the immune system to prevent infection, offering a potential clue to the cause of autoimmune disorders like rheumatoid arthritis and multiple sclerosis. "The findings shed light on the complex balance between beneficial and harmful bacteria in the gut," said Prof...
Biopsies Reveal Nature Of Brain Lesions Early In MS Progression, Countering Conventional Wisdom
Working together, researchers at Cleveland Clinic and Mayo Clinic have for the first time examined early multiple sclerosis (MS) brain lesions in the cerebral cortex. These lesions are thought to be critical to MS progression and the researchers found that the lesions are distinctly different than previously speculated, giving clues to better disease management...
Mayo Clinic Collaboration Finds Multiple Sclerosis Often Starts In Brain's Outer Layers
Multiple sclerosis (MS) may progress from the outermost layers of the brain to its deep parts, and isn't always an "inside-out" process as previously thought, reported a new collaborative study from researchers at the Mayo Clinic and the Cleveland Clinic...
Promising Multiple Sclerosis Treatment Targets Immune Cells To Increase Neuroprotection
Laquinimod is an orally available synthetic compound that has been successfully evaluated in phase II/III clinical studies for the treatment of relapsing-remitting multiple sclerosis (RRMS)...
CCSVU And MS Risk Factors Are Similar
At the University of Buffalo, researchers conducted the first investigation to research risk factors for the vascular condition - chronic cerebrospinal venous insufficiency (CCSVI). The team investigated risk factors for CCSVI in volunteers without neurological disease and found a remarkable similarity between CCSVI and possibility of verified risk factors for multiple sclerosis (MS)...
Risk Factors For CCSVI Are Similar To Risk Factors For Developing MS
The first study to investigate risk factors for the vascular condition called CCSVI (chronic cerebrospinal venous insufficiency) in volunteers without neurological disease has identified what the researchers call a remarkable similarity between this condition and possible or confirmed risk factors for multiple sclerosis (MS)...
Risk Factors For Chronic Cerebrospinal Venous Insufficiency Are Similar To Risk Factors For Developing Multiple Sclerosis: UB Study
Summary: A vascular condition called chronic cerebrospinal venous insufficiency (CCSVI), which has attracted global attention as possibly being correlated with MS has, for the first time, been studied for the presence of risk factors in subjects who do not have a neurological disease...
Risk Factors For CCSVI Are Similar To Risk Factors For Developing MS
The first study to investigate risk factors for the vascular condition called CCSVI (chronic cerebrospinal venous insufficiency) in volunteers without neurological disease has identified what the researchers call a remarkable similarity between this condition and possible or confirmed risk factors for multiple sclerosis (MS)...
Higher Patient Adherence To Disease Modifying Therapies Reduced Costs For MS Patients
Avi Dor, Ph.D...
Modified Story Memory Technique Used To Treat Learning And Memory Deficits In MS
John DeLuca, PhD, Vice President for Research at Kessler Foundation presented findings on the use of a behavioral technique for cognitive rehabilitation in people with multiple sclerosis (MS). Lead investigator was Nancy Chiaravalloti, PhD, director of the Neuropsychology & Neuroscience Laboratory at Kessler Foundation...
New Candidate Gene For Lou Gehrig's Disease Revealed By Genetic Screening In Yeast
Amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, is a universally fatal neurodegenerative disease. Mutations in two related proteins, TDP-43 and FUS, cause some forms of ALS. Specifically, these two proteins are RNA-binding proteins that connect to RNA to regulate the translation of proteins and other cellular functions such as RNA splicing and editing...
Mouse Model Offers Potential New Drug Target In Lou Gehrig's Disease
Two proteins conspire to promote a lethal neurological disease, according to a study published online this week in the Journal of Experimental Medicine*. Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a devastating neurodegenerative disorder that results in progressive loss of motor function and ultimately death...